A network meta-analysis shows that combining platelet-rich plasma with hyaluronic acid offers superior pain relief and functional improvement for knee osteoarthritis compared to PRP alone or other combinations.
Platelet-rich plasma provides greater pain relief and functional improvement than hyaluronic acid for knee osteoarthritis: a systematic review and meta-analysis of randomized controlled trials.
A meta-analysis shows intra-articular platelet-rich plasma improves pain and function more than hyaluronic acid in knee osteoarthritis, especially when using leukocyte-poor formulations in early-stage disease.